Head coach Murray Houston has made a number of changes to the matchday 23 ahead of the home game.
Skipper India Daley moves to hooker and is joined by seasoned Aishling O'Connell and Sophie Barrett at tighthead and loosehead prop respectively.
Vice-captain Brenda Barr returns at lock and is joined by Ellen Patterson.
Rounding off the forward pack is Moya Hill and Rebecca Beacom in the flanks, with Stacey Sloan at Number 8.
The out-half partnership sees two changes, with Sophie Meeke at scrum-half and Abby Moyles returning from injury at fly-half.
Kelly McCormill and Siobhán Sheerin run out in the midfield.
Niamh Marley stays at wing this week, and is joined by debutante, Ciara Fitzsimons.
Kate Farrell-McCabe completes the starting XV at full-back.
Replacement cover comes from Megan Simpson, Bronach Cassidy, Sophie McAlister, Lauren Darley and Georgia Boyce, with Ciara O'Donnell, Farrah Cartin-McCloskey and Katie Gilmour all hoping to make their debut.
Ulster Rugby
15 Kate Farrell-McCabe (Suttonians RFC)<br>
14 Ciara Fitzsimons\* (Queens RFC)<br>
13 Siobhán Sheerin (Clogher Valley RFC) <br>
12 Kelly McCormill (Monaghan RFC) <br>
11 Niamh Marley (Cooke RFC) <br>
10 Abby Moyles (UL Bohemians RFC)<br>
9 Sophie Meeke (Enniskillen RFC)
8 Stacey Sloan (Cooke RFC)<br>
7 Rebecca Beacom (Enniskillen RFC)<br>
6 Moya Hill (Enniskillen RFC) <br>
5 Brenda Barr (VC) (Suttonians RFC) <br>
4 Ellen Patterson (Queens RFC) <br>
3 Sophie Barrett (Enniskillen RFC)<br>
2 India Daley (C) (Enniskillen RFC)<br>
1 Aishling O'Connell (Monaghan RFC)
Replacements
16 Megan Simpson (Cooke RFC)<br>
17 Bronach Cassidy (Queens RFC)<br>
18 Sophie McAlister (Ballymena RFC)<br>
19 Lauren Darley (Queens RFC)<br>
20 Ciara O'Donnell\* (Enniskillen RFC)<br>
21 Georgia Boyce (Enniskillen RFC)<br>
22 Farrah Cartin-McCloskey\* (Enniskillen RFC)<br>
23 Katie Gilmour\* (Cooke RFC)
\**denotes uncapped*