Skipper India Daley returns to the back row at number 8, with Ruby Starrett moving to openside flanker, and Moya Hill joining at blindside.
Vice-captain Brenda Barr and Lauren Darley retun to the forward pack in the second row.
Houston has made one change in the front row, with Ava Fannin running out at tighthead prop. Queen's duo Sarah Roberts and Maebh Clenaghan remain unchanged at loosehead and hooker.
The out-half partnership remains unchanged, Georgia Boyce at scrum-half and Lauren Farrell-McCabe at fly-half.
Siobhán Sheerin and Tara O'Neill run out in the midfield.
Niamh Marley moves from full-back to wing this week, and is joined by Lucy Thompson once again.
Newcomer Kate Farrell-McCabe completes the starting XV at full-back.
Head coach, Murray Houston opts for a 6:2 split on the bench, with Cara McLean, Megan Simpson, Sophie Barrett, Rebecca Beacom, Katie Hetherington and Stacey Sloan providing the forward cover. Kelly McCormill once again provides backs cover, with Sophie Meeke joining her.
Ulster Rugby
15 Kate Farrell-McCabe (Suttonians RFC)<br>
14 Lucy Thompson (Enniskillen RFC) <br>
13 Siobhán Sheerin (Clogher Valley RFC) <br>
12 Tara O'Neill (Cooke RFC) <br>
11 Niamh Marley (Cooke RFC) <br>
10 Lauren Farrell-McCabe (Suttonians RFC) <br>
9 Georgia Boyce (Cooke RFC)
8 India Daley (C) (Enniskillen RFC) <br>
7 Ruby Starrett (Queens RFC) <br>
6 Moya Hill (Enniskillen RFC) <br>
5 Brenda Barr (VC) (Suttonians RFC) <br>
4 Lauren Darley (Queens RFC) <br>
3 Ava Fannin (Blackrock RFC) <br>
2 Maebh Clenaghan (Queens RFC) <br>
1 Sarah Roberts (Queens RFC)
Replacements
16 Cara McLean (Larne RFC) <br>
17 Megan Simpson (Cooke RFC)<br>
18 Sophie Barrett (Enniskillen RFC) <br>
19 Rebecca Beacom (Enniskillen RFC) <br>
20 Katie Hetherington (Clogher Valley RFC) <br>
21 Sophie Meeke (Enniskillen RFC)<br>
22 Kelly McCormill (Monaghan RFC) <br>
23 Stacey Sloan (Cooke RFC)