Head coach Murray Houston has named his starting 23.
Following on from last week's opener, slight changes to the fron row have been made with Bronach Cassidy starting at loosehead, India Daley at hooker, and Sophie Barrett at tighthead.
The second row is also tweaked, seeing the experienced Brenda Barr alongside Cara O’Kane stepping out on her first start as lock.
Moya Hill and Maebh Clenaghan will form the dynamic back row duo, with the powerful Brittany Hogan leading the side from number eight.
Captain Kathryn Dane will distribute from scrum-half, while Abby Moyles returns to pull the strings at fly-half.
The midfield partnership will feature Peita McAlister at inside centre and last week's try-scorer, Tara O'Neill at outside centre.
Catherine Martin makes a highly anticipated debut on the left wing, with Lucy Thompson on the right. Lauren Farrell-McCabe continues at full-back.
Houston sticks to 5:3 split amongst the replacements, with with Christy Hill, Megan Brodie, Ava Fannin, Gemma McCamley and Stacey Sloan as forward replacements, with Rachael McIlroy, Paige Smyth and Vicky Irwin ready to make an impact for the backs.
Megan Simpson is reserve for this weekend's team.
Ulster Rugby v Connacht Rugby, Saturday 17 August (kick-off 2.30pm)
(15-9): Lauren Farrell - McCabe, Lucy Thompson, Catherine Martin, Tara O'Neill, Peita McAlister, Abby Moyles
Kathryn Dane (C)
(1-8): Bronach Cassidy, India Daley, Sophie Barrett, Brenda Barr, Cara O'Kane, Moya Hill, Maebh Clenaghan, Brittany Hogan (VC)
Replacements: Christy Hill, Megan Brodie, Ava Fannin, Gemma McCamley, Stacey Sloan, Rachael McIlroy, Paige Smyth, Vicky Irwin
Reserve: Megan Simpson
Our opposition:
(15-9) Meabh Deely, Clara Barrett, Orla Dixon, Éabha Nic Dhonnacha, Laoise McGonagle, Nicole Fowley (CC), Grainne Moran
(1-8) Ella Burns, Lily Brady, Megan Collis, Karly Tierney, Grace Browne Moran, Faith Oviawe, Beibhinn Gleeson, Shannon Touhey (CC)
Replacements: Stacey Hanley, Hope Lowney, Roisin Maher, Jemima Adams Verling, Rosie Searle, May Goulding, Ava Ryder, Hannah Clarke
Where to watch
The game will be available to watch on BBC iPlayer and TG4.